https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Nucleotide excision repair of UVA-induced DNA damage: regulation in sunlight-induced melanoma https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21077 Wed 11 Apr 2018 10:47:55 AEST ]]> Nucleotide excision repair deficiency in melanoma in response to UVA https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24616 40 % of lesions remained in melanoma cell lines at 48 h. This was coupled with a delayed and reduced induction of GGR component XPC in melanoma cells, independent of p53. Conclusion: These findings support that NER activity is reduced in melanoma cells due to deficient GGR. Further investigation into the role of NER in UVA-induced melanomagenesis is warranted and may have implications for melanoma treatment.]]> Wed 09 Feb 2022 15:53:41 AEDT ]]>